Jon Voight in Midnight Cowboy (1969)

Texas greenhorn Joe Buck arrives in New York City for the first time. Preening himself as a real “hustler”, he finds that he is the one getting “hustled” until he teams up with down-and-out but resilient outcast Ratso Rizzo. The initial “country cousin meets city cousin” relationship deepens. In their efforts to bilk a hostile world rebuffing them at every turn, this unlikely pair progress from partners in shady business to comrades. Each has found his first real friend.